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Deep posteromedial cortical rhythm in dissociation. Deep brain optogenetics without intracranial surgery. Nature Biotechnology. Multiple convergent hypothalamus-brainstem circuits drive defensive behavior. Nature Neuroscience.
Deep posteromedial cortical rhythm in dissociation. Deep brain optogenetics without intracranial surgery. Nature Biotechnology. Multiple convergent hypothalamus-brainstem circuits drive defensive behavior. Nature Neuroscience. Genetically targeted chemical assembly of functional materials in living cells, tissues, and animals.
Cortical layer-specific critical dynamics triggering perception. Neuronal dynamics regulating brain and behavioral state transitions. Thirst regulates motivated behavior through modulation of brainwide neural population dynamics. Interacting neural ensembles in orbitofrontal cortex for social and feeding behavior. Crystal structure of the natural anion-conducting channelrhodopsin Duie. Structural mechanisms of selectivity and gating in anion channelrhodopsins.
Three-dimensional intact-tissue sequencing of single-cell transcriptional states. Hydrogel-tissue chemistry: principles and applications. Ancestral circuits for the coordinated modulation of metbod state. The form and function of channelrhodopsin.
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Rabies screen reveals GPe control of cocaine-triggered plasticity. Thirst-associated preoptic neurons encode an dukf motivational drive. Molecular and circuit-dynamical identification of top-down neural mechanisms for restraint of reward seeking.
Science Translational Medicine. Scientific Reports. Optical and chemical discoveries recognized for impact on biology and psychiatry. EMBO Reports.
Global representations of goal-directed behavior in distinct cell types of mouse neocortex. Integration of djke with complementary methodologies in systems neuroscience. Nature Reviews Neuroscience. In search of lost time. Gamma oscillations organize top-down alling to hypothalamus and enable food seeking. A look inside the brain. Scientific American.
Nucleus accumbens D2R cells al prior outcomes and control risky decision-making. Targeting neural circuits. Optogenetic approaches addressing extracellular modulation of neural excitability. Communication in neural circuits: tools, opportunities, and challenges. Hypothalamic control of male aggression-seeking behavior. Multiplexed intact-tissue transcriptional analysis at cellular resolution. Simultaneous mdthod measurement of circuit dynamics at multiple sites across the mammalian brain.
Nature Methods. Illuminating next-generation brain therapies. Prefrontal cortical regulation of brainwide circuit dynamics and reward-related behavior. Structural foundations of optogenetics: determinants of channelrhodopsin ion selectivity. SPED light sheet microscopy: fast mapping of biological system structure and function. Extended field-of-view and increased-al 3D holographic illumination with time-division multiplexing. Optics Express.
Basomedial amygdala mediates top-down control of anxiety and fear. Thalamic control of sensory selection in divided attention. Projections from neocortex mediate top-down control of memory retrieval Nature. Optogenetics: 10 years of microbial opsins in neuroscience. Expanding the optogenetics toolkit.
Science, VolumeIssue Optogenetics and the Circuit Dynamics of Psychiatric Disease. B ; DOI: November Optical Neural Interfaces. June Targeting cells with single vectors using multiple-feature Boolean logic Nature Methods. Nature Protocols. April Circuit dynamics of adaptive and maladaptive behavior. January October Light microscopy dule of connections in the intact brain.
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Trends in Cognitive Sciences. A unique population of ventral tegmental area neurons inhibits the lateral habenula to promote reward.
Engineering approaches to illuminating brain structure and dynamics. Causal interactions between fronto-parietal central executive and default-mode networks in humans. Optogenetic activation of an inhibitory network enhances feedforward functional connectivity in auditory cortex.
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June 7, Mefhod causal link between prediction errors, dopamine neurons and learning. Advance Online Pulbication May J Neuroscience. May 1, March 20, Structural and molecular interrogation of intact biological systems. Advance Online Publication Apr Diverging neural pathways assemble a behavioural state from separable features in anxiety. Advance Online Publication Mar Optogenetics in the behaving rat: integration of diverse new technologies in a vital animal model.
Dopamine neurons modulate neural encoding and expression of depression-related behaviour. Advance Online Publication Dec. Rapid regulation of depression-related behaviours by control of midbrain dopamine neurons. A prefrontal cortex-brainstem neuronal projection that controls response to behavioural challenge. Closed-loop optogenetic control of thalamus as a tool for interrupting seizures after cortical injury.
Nat Neurosci. Epub Nov 7. Two-photon optogenetic toolbox for fast inhibition, excitation and bistable modulation.
Nat Methods. Advance Online Publication Nov Two-photon optogenetics of dendritic spines and neural circuits. Epub Nov Optogenetics and psychiatry: applications, challenges, and opportunities. Biol Psychiatry. Epub Apr When the electricity and the lights go out: transient changes in excitability. Cell Rep. Epub Jul Neuronal circuitry mechanism regulating adult quiescent neural stem-cell fate decision.
Optogenetic inhibition of cocaine seeking in rats. Addict Biol.